Scott is a middle age contractor who suffers from OCD and is a severe germaphobe who compulsive cleans his house. Helen is single mother of three whose compulsive "checking" spiked after her father's death in a car accident.

Traci struggles with both germaphobia and claustrophobia. She is constantly cleaning and is frightened to get on an elevator. She can't even enjoy home-cooked meals without fearing illness. Meanwhile, Judi is a hoarder.