The team searches for two gunmen who are taking their COVID-related desperation and rage out on their perceived oppressors, and Jess' father returns to his son's life.

The team race to find a hacker who took control of a family car, and caused a fatal crash, then sent a ransom demand; $1 million, or he will do it again.

After witnessing her husband's murder, a woman is kidnapped from her home and a mysterious stash of money hidden in her floor is taken; Jess realizes there may be a connection to a past case, the need to find the kidnapper becomes personal.

Four Mohawk youths killed near the Canadian border, presumably by the New Patriots, a fringe military group patrolling the US-Canadian border.

Following a failed home invasion, the team must track down a pair of killers who are holding the surviving members of the family hostage.

Soon after a suspect escapes trial and goes on a murder spree, the fugitive task force partners with bail bondsperson Jackie Ward in order to track him down; Jess continues struggling to move forward in his love life.

The team chases an unlikely serial killer whose endgame takes a shocking turn. Hana returns from medical leave; Jess and Sarah's relationship continues to evolve.

After Crosby's old army buddy is attacked in an apparent drug deal gone wrong, the team's quest for answers uncovers a dangerous web of conspiracy; Jess questions his relationship with Sarah after an unexpected encounter.

After a double murder takes place in a small town, the team goes after the vigilante who relies on internet sleuths to exact revenge on suspects in the name of justice.

When a young man accidentally shoots a cop in self-defense and goes on the run, the team members find themselves in a moral dilemma on the best way to carry out justice; Barnes and her wife struggle with their plans to have another child.

The team tracks two brothers set on getting revenge against members of the company that caused their town's environmental destruction. Also, Sarah meets the rest of the LaCroix family, including Jess' sister, Louise.

The team heads to D.C. to protect Ortiz's former informant after a hitman tries to kill her. Also, Sarah helps Jess' family prepares for Byron and Marie's last-minute wedding on Jess' farm.

Jess and the Most Wanted team head to Tennessee to track down an undercover DEA agent who appears to have turned dirty amid a major drug ring operation. Also, Sarah wonders if it was a mistake to move in with Jess and Tali so soon.