Eleanor presses Franklin to act more boldly against the Great Depression. After Nixon's resignation, Betty becomes First Lady days before a state dinner. Before Barack's inauguration, Michelle faces opposition from his transition team.

Young Eleanor attends her coming out party in New York where she meets cousin Franklin. In Michigan, young Betty is courted by hotshot lawyer Jerry. At a Chicago law firm, young Michelle meets summer intern Barack, interested in politics.

Franklin's marital indiscretions push Eleanor to socialize with more political women. A stubborn shoulder injury begins Betty's troubled history with pain medication. Michelle vows to hold Chicago's inadequate healthcare system to task.

Eleanor holds the White House's first all-female press conference and grows closer to journalist Lorena Hickock. Betty publicly announces her breast cancer diagnosis. Michelle prompts new legislation with her healthy school lunch program.

Eleanor, Betty and Michelle's daring stances put them in the spotlight.

Eleanor doubles down on her efforts to confront racism. Betty helps Jerry secure the Republican nomination while her problems with addiction worsen. Michelle grieves after recent gun violence tragedies and advocates for legislative action.

Eleanor forces Franklin's hand in assisting Jewish refugees fleeing Nazi Germany. Jerry spends his retirement on the road, Betty seeks out new party companions at home. Despite Barack's hesitations, Michelle directly speaks out about race.

Eleanor rallies the country as the U.S. enters WW II. After Betty's addiction spirals, Jerry and her family intervene. Michelle joins Hillary Clinton on the 2016 presidential campaign trail to advocate for the dignity of American women.