A new head of the ED is announced and not everyone likes the choice. Dr. Manning makes a stand for her patient which has repercussions. Dr. Charles tends to his family

Dr. Choi helps a patient with chronic pain find a solution. Dr. Halstead considers a new path. Dr. Charles and Anna bond over a scary situation.

Halstead runs into trouble when one of his trial patients falls ill. His own stress and symptoms have Choi struggling to get through the day.

Ethan hires an old Navy colleague to join him in the ED. A final custody hearing threatens to separate Daniel and his daughter. Maggie must make a choice that will change Auggie's life.

As Manning deals with her own trauma, she steps in to help a mother in need. Archer continues to stir the pot with more than one doctor. A patient comes to Med needing immediate treatment but doesn't want it from them.

Crockett deals with a patient who ends up having more in common with him than he thinks. Will and Ethan clash over a pregnant patient with an irregular heartbeat.

Ethan teams up with an unexpected person to treat a famous tennis player who is afraid his career might be over. Goodwin's new protocols cause a stir.

Archer and Choi go in to the field but the scene brings war flashbacks. Carol's condition worsen and Manning tries to get her enrolled in Halstead's drug trial.

An auto accident sends Goodwin into a spiral as she tries to help a young boy and his mother. Natalie's secretive behavior begins to draw the attention of Dr. Marcel and Dr. Halstead.

Third-year med students begin their rotation in the ED and Maggie keeps a careful eye on one of them. Natalie, whose mom's health takes another decline, tries to cover up how she broke the rules to treat her.

Crockett worries he made a surgical error when a recent transplant patient comes in with complications. Carol is once again in distress. Will and Natalie must take action to right their wrong.

Carol receives a second chance at life when a new heart becomes available. Ethan and Dean find themselves in hot water with an old patient. Will faces the consequences of the stolen trial medication.