Guided by an angel, Colette, the "Chosen One," sets off on a journey to regenerate her dying world.

Beset by assassins, Colette and her childhood friends, Lloyd and Genis, learn the truth about regenerating their world.

Lloyd is rocked by a revelation about his true father, even as her masters the powerful stone his late mother left him.

Lloyd, Genis and their allies do everything they can to keep Colette from being turned into an angel, even if it costs them the world.

As Lloyd and company visit the twin world of Tethe'alla to search for a cure to Colette's disease, Angel Toxicosis, they meet her counterpart Chosen One, Zelos, who has an agenda of his own.

As Colette's fate becomes more complicated, Lloyd gains a new ally in Regal Bryant, the former president of a conglomerate who had until recently been imprisoned for murder.

Former assassin and current ally Sheena may be the key to defeating their enemy by forming a pact with a powerful spirit, except the last time she did it.

Lloyd and his comrades make an assault on the "Nest of Flying Dragons" in an attempt to rescue Colette, but aside from an army of dragons and a behemoth-sized dragon, Lloyd's master swordsman father stands in his way.

A mysterious boy with the same name as an ancient hero shows up and quickly befriends fellow secret half-elf Genis, but trouble soon ensues.

As the journey's end nears, a pact with a powerful spirit must be broken while Lloyd and his comrades race to the top of the Tower of Salvation to stop their true enemy once and for all.

The final battle may be over, but Lloyd and his allies only have one shot to save two worlds.