Kyle returns to Rome with Amber to look for Sydney and check up on Megan.

Chief Giles helps Kyle pursue a more aggressive strategy to deal with the number of possession cases in Rome, and his efforts see him encounter a new foe.

A dangerous fugitive on the loose threatens the town of Rome, as well as Reverend Anderson's sanity. Kyle struggles with a new understanding of where his powers--and curse--originate. Megan and Holly attempt to rebuild their lives.

Kyle gets closer to finding Sidney while Anderson discovers an unexpected potential ally. A prominent member of the Rome community is revealed to be an agent of the possessed and few characters will escape his plan unscathed.

When Kyle is brought to the ER after his fight with the demon in Chief Giles, he dies on the operating table and goes to a whole other place.

With Simon and Kyle Barnes together, Rome faces a battle against the demonic forces possessing its people. At the same time, a pregnant Megan struggles to escape Dr. Park and Blake's clutches.